| Dean | Term |
|---|---|
| Benjamin Rush | 1805 |
| Philip Syng Physick | 1808 |
| John Syng Dorsey | 1809 |
| Philip Syng Physick | 1814 |
| Nathaniel Chapman | 1815 |
| Thomas Chalkley James | 1815 |
| Caspar Wistar | 1816 |
| Nathaniel Chapman | 1817 |
| John Redman Coxe | 1819 – 1822 |
| William Edmonds Horner | 1822 – 1852 |
| Joseph Carson | 1852 – 1856 |
| Robert E. Rogers | 1856 – 1877 |
| Joseph Leidy | 1877 – 1888 |
| James Tyson | 1888 – 1892 |
| John Marshall | 1892 – 1902 |
| Charles Harrison Frazier (acting 1902 – 1903) | 1902 – 1909 |
| Allen J. Smith | 1909 – 1912 |
| William Pepper III | 1912 – 1945 |
| Isaac Starr | 1945 – 1948 |
| John McK. Mitchell | 1948 – 1962 |
| Samuel Gurin | 1962 – 1969 |
| Alfred Gellhorn | 1969 – 1973 |
| Edward Stemmler (acting 1974 – 1975) | 1974 – 1988 |
| Arthur K. Asbury (acting) | 1988 – 1989 |
| William N. Kelley | 1989 – 2000 |
| Peter G. Traber (interim) | 2000 – 2001 |
| Arthur H. Rubenstein | 2001 – 2011 |
| J. Larry Jameson | 2011 – 2023 |
| Jonathan A. Epstein (interim 2023 – 2025) | 2023 – present |
University Leaders Deans of the Schools Deans of the School of Medicine, 1805-present
Benjamin Rush, c. 1800